Cancer Clinical Trials
A clinical trials program is an essential part of a true cancer center. All of the current treatments for oncology patients today have been developed from yesterday’s trials. Our program enables patients in our community to receive potential direct benefit of new drugs and treatment pathways while sleeping in their own bed at night, but also indirectly builds the science for future patients who may be their loved ones.
What are clinical trials?
According to the American Cancer Society, clinical trials are studies in which people volunteer to test new drugs or devices. Doctors use clinical trials to learn whether a new treatment works and is safe for people. These kinds of studies are needed to develop new treatments for serious diseases like cancer.
Clinical trials are vital in studying all aspects of medicine, not just cancer. The stakes may seem higher when researching medicines to treat cancer, but all new treatments (drugs and medical devices) must go through clinical trials before being approved by the FDA (Food and Drug Administration).
Breast Cancer Trials
Alliance-GET SET: This is a study for women with stage I-III hormone positive, HER-2 negative invasive breast cancer who have completed their surgery, chemotherapy, and radiation, and are prescribed endocrine therapy. This trial is aimed to help assist patients in remembering to take their endocrine therapy either via text message, motivational counseling or standard care. Learn More.
GS-US-586-6144: This study is for patients with locally advanced or metastatic triple negative breast cancer (hormone negative and HER-2 negative). The purpose of this study is to evaluate an investigational new drug, Magrolimab, in combination with chemotherapy. Learn More.
UF Hypomagnesemia: This study is for patients with HER-2 positive breast cancer who have been prescribed Pertuzumab (Perjeta). The aim of this study is being done to see if Pertuzumab is associated with lower levels of magnesium.
GI Cancer Trials
US-STO-PANC-004: TMH is partnering with the University of Florida to offer this trial to our patients who have been diagnosed with resectable or borderline resectable pancreatic cancer. This trial is looking at the addition of ONIVYDE in combination with 5-FU and Oxaliplatin in the preoperative (neoadjuvant) treatment of pancreatic adenocarcinoma. Learn More.
BESPOKE CRC: This study is for patients with colorectal cancer who have undergone surgery or will be undergoing surgery and will receive the Signatera test. This study aims to observe the outcome of patients receiving Signatera testing, if their test results effected what treatments they received and health related quality of life. Learn More.
Hematologic Cancer Trials
CLL Registry: This study is for patients diagnosed with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who are starting treatment either with Acalabrutinib (Calquence) or Ibrutinib (Imbruvica). The goal is to understand patients’ health related quality of life. Learn More.
Multiple Cancer Trials
GS-US-548-5918: This study is for patients with metastatic non-small cell lung cancer (NSCLC), metastatic small cell lung cancer (SCLC) and metastatic urothelial cancer (UC). The purpose of this study is to evaluate an investigational new drug, Magrolimab, in combination with chemotherapy. Learn More.
iCaRe2 Registry: This study is for patients who have been diagnosed with cancer. The goal of this registry is to collect information about a patient’s cancer diagnosis and health related quality of life. Learn More.
